Zebrafish small molecule screens: Taking the phenotypic plunge
نویسندگان
چکیده
منابع مشابه
Zebrafish small molecule screens: Taking the phenotypic plunge
Target based chemical screens are a mainstay of modern drug discovery, but the effectiveness of this reductionist approach is being questioned in light of declines in pharmaceutical R & D efficiency. In recent years, phenotypic screens have gained increasing acceptance as a complementary/alternative approach to early drug discovery. We discuss the various model organisms used in phenotypic scre...
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ژورنال
عنوان ژورنال: Computational and Structural Biotechnology Journal
سال: 2016
ISSN: 2001-0370
DOI: 10.1016/j.csbj.2016.09.001